Stealth Supersymmetry

We present a broad class of supersymmetric models that preserve R-parity but lack missing energy signatures. These models have new light particles with weak-scale supersymmetric masses that feel SUSY breaking only through couplings to the MSSM. This small SUSY breaking leads to nearly degenerate fermion/boson pairs, with small mass splittings and hence small phase space for decays carrying away invisible energy. The simplest scenario has low-scale SUSY breaking, with missing energy only from soft gravitinos. This scenario is natural, lacks artificial tunings to produce a squeezed spectrum, and is consistent with gauge coupling unification. The resulting collider signals will be jet-rich events containing false resonances that could resemble signatures of R-parity violation. We discuss several concrete examples of the general idea, and emphasize gamma + jet + jet resonances, displaced vertices, and very large numbers of b-jets as three possible discovery modes.Comment: 12 pages, 4 figure

Light Sterile Neutrinos and Short Baseline Neutrino Oscillation Anomalies

We study two possible explanations for short baseline neutrino oscillation anomalies, such as the LSND and MiniBooNE anti-neutrino data, and for the reactor anomaly. The first scenario is the mini-seesaw mechanism with two eV-scale sterile neutrinos. We present both analytic formulas and numerical results showing that this scenario could account for the short baseline and reactor anomalies and is consistent with the observed masses and mixings of the three active neutrinos. We also show that this scenario could arise naturally from an effective theory containing a TeV-scale VEV, which could be related to other TeV-scale physics. The minimal version of the mini-seesaw relates the active-sterile mixings to five real parameters and favors an inverted hierarchy. It has the interesting property that the effective Majorana mass for neutrinoless double beta decay vanishes, while the effective masses relevant to tritium beta decay and to cosmology are respectively around 0.2 and 2.4 eV. The second scenario contains only one eV-scale sterile neutrino but with an effective non-unitary mixing matrix between the light sterile and active neutrinos. We find that though this may explain the anomalies, if the non-unitarity originates from a heavy sterile neutrino with a large (fine-tuned) mixing angle, this scenario is highly constrained by cosmological and laboratory observations.Comment: 25 pages, 6 figure

CoNIC Challenge: Pushing the Frontiers of Nuclear Detection, Segmentation, Classification and Counting

Nuclear detection, segmentation and morphometric profiling are essential in helping us further understand the relationship between histology and patient outcome. To drive innovation in this area, we setup a community-wide challenge using the largest available dataset of its kind to assess nuclear segmentation and cellular composition. Our challenge, named CoNIC, stimulated the development of reproducible algorithms for cellular recognition with real-time result inspection on public leaderboards. We conducted an extensive post-challenge analysis based on the top-performing models using 1,658 whole-slide images of colon tissue. With around 700 million detected nuclei per model, associated features were used for dysplasia grading and survival analysis, where we demonstrated that the challenge's improvement over the previous state-of-the-art led to significant boosts in downstream performance. Our findings also suggest that eosinophils and neutrophils play an important role in the tumour microevironment. We release challenge models and WSI-level results to foster the development of further methods for biomarker discovery